Bronchiectasis is destruction and widening of the large airways. If the condition occurs at birth, it is called congenital. If it develops later in life, it is acquired bronchiectasis. This condition is often caused by recurrent inflammation or infection of the airways and can begin in childhood, develop after a more severe lung infection or be caused by inhaling a foreign object. Cystic fibrosis causes about a third of all bronchiectasis cases in the United States. Certain genetic conditions can also cause the condition, including: primary ciliary dyskinesia and immunodeficiency syndromes. Bronchiectasis can also be caused by routinely breathing in food particles while eating. Symptoms may include: bluish skin color, noticeable breath odor, chronic cough, clubbing of fingers, coughing up blood, a cough that gets worse when lying on one side, fatigue, paleness, shortness of breath that gets worse with exercise, weight loss and wheezing.